Risk adjusted net present value: What is the current valuation of Novo Nordisk’s NNC-6019?
Risk adjusted net present value: What is the current valuation of Novo Nordisk’s NNC-6019?
NNC-6019 is a monoclonal antibody commercialized by Novo Nordisk, with a leading Phase II program in Amyloid Cardiomyopathy. According to Globaldata, it is involved in 3 clinical trials, of which 1 was completed, 1 is ongoing, and 1 is planned. Smarter leaders trust GlobalData The revenue for NNC-6019 is expected to reach an annual total of $19 mn by 2039 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress. NNC-6019 Overview PRX-004 is under development for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM) and familial amyloid polyneuropathy. It is administered through intravenous route. The therapeutic candidate is a monoclonal antibody which acts by targeting misfolded transthyretin (TTR) protein. Novo Nordisk Overview Novo Nordisk, a subsidiary of Novo Holdings AS, is a healthcare company focused on discovering, developing, and manufacturing of innovative biological medicines. It focuses on advancing drugs for the treatment of diabetes and other serious chronic conditions, including hemophilia, human growth hormone (HGH) disorders, rare blood and rare endocrine diseases, and obesity. The company’s portfolio includes pre-filled delivery systems for insulin; glucagon hypokit; cartridge; needles; vials; insulin; estradiol for hormone replacement; recombinant drugs for hemophilia; glucagon; and oral antidiabetic agents. The company markets its products through subsidiaries in North America, Europe, Asia, Latin America, Africa, the Middle East and Australia. Novo Nordisk is headquartered in Bagsvaerd, Denmark. The company reported revenues of (Danish Krone) DKK176,954 million for the fiscal year ended December 2022 (FY2022), an increase of 25.7% over FY2021. In FY2022, the company’s operating margin was 42.3%, compared to an operating margin of 41.7% in FY2021. In FY2022, the company recorded a net margin of 31.4%, compared to a net margin of 33.9% in FY2021. The company reported revenues of DKK54,300 million for the second quarter ended June 2023, an increase of 1.7% over the previous quarter. For a complete picture of NNC-6019’s valuation, This content was updated on 15 September 2023 Give your business an edge with our leading industry insights. From Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors. , the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article. To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company. The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s . Smarter leaders trust GlobalData The gold standard of business intelligence.
Publish Date : 2023-10-04 01:26:41
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